Abstract

PHARMACOGNOSTIC, PHYTOCHEMICAL, PHYSIOCHEMICAL AND ANTISPASMODIC PROPERTIES OF LEAVES OF CISSAMPELOS PAREIRA L.

Sushma Singh*, Shweta Yadav, Kakli Rai and Rishabh Chaurasiya

.

Abstract

Cissampelos pareira Linn which is commonly known as velvet leaf and pareira brava belongs to the family Menispermaceae. The leaves of Cissampelos pareira has traditionally been used for the treatment of abdominal pain and diarrhoea. However, scientific data on the biological activities of plants are limited basis. Therefore, the purpose of the present study was to evaluate the antispasmodic effects of Cissampelos pareira leaf constituents on rat ileum. Antispasmodic activity was assessed by the interpolation method on isolated chicken ileum. Effects of acetylcholine, methanolic extract of Cissampelos pareira leaves and acetylcholine along with methanolic leaves extract were studied on isolated chicken ileum. The present study results revealed that methanolic leaves extract of Cissampelos pareira Linn showed promising antispasmodic action on excised chicken ileum.

Keywords: Cissampelos pareira, Pharmacognostic, Phytochemical, Physiochemical, Antispasmodic.