Abstract

APPLICATION OF 22 FACTOIRAL DESIGN IN THE FORMULATION AND EVALUATION OF SUNSCREEN CONTAINING NON NANO ZINC OXIDE AND POLYPODIUM LEUCOTOMOS

R. Ramya*, Dr. G. Mariyappan, M. Venkatesan, R. Rajadurai, K. Vidhya and M. Prem Kumar

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Abstract

Sun exposure affects the skin in many ways. In the short term it can leads to reddening and tanning. In the long term effect of UV radiation which are irreversible and often cause sunburn, wrinkling, and skin cancer. For the reason, sun protection has become, a very important issue today. UV filter ingredients that can effectively protect the skin from UV radiation. To increases the Sun Protection Factor, value the incorporation of chemical and physical UV filters this turns to toxicity. In this research our aim is to formulate and evaluate the sunscreen containing polypodium leucotomos and non-nano zinc oxide. Before the formulation, preformulation study of polypodium leucotomos and non-nano zinc oxide describes here includes macroscopic observation, particle size, hydroscopicity, flow property. Determine the main effect, interaction effect and surface plot. The formulated sunscreen was then evaluated for its colour, odour, PH, spreadability, invitro SPF etc.

Keywords: Sun protection factor, non nano zinc oxide, polypodium leucotomos, UV filter, invitro SPF.