Abstract

CORRELATION BETWEEN OXIDATIVE STRESS AND GLYCATED HEMOGLOBIN AND LP (A) IN PATIENTS WITH DIABETES MELLITUS

Ahmed M. Ahmed*

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Abstract

Oxidative stress (OS) is well defined as an imbalance between free radicals and antioxidants defense in human body which can be lead to inflammation across the body and its serious particularly in heart and brain. In this cross-sectional study, blood samples were collected from 40 type 1 diabetes (T1DM) and 60 type 2 (T2DM) compared with 50 healthy subjects as controls, glycation and lipids profiles were measured, GPx and SOD antioxidants enzymes were measured as well as MDA and Lp(a) were measured and compared across study groups. Glycemic, Lp(a), GPx, SOD and MDA were high in patient than controls (p>0.001). In addition, Lp(a), GPx and MDA were higher in T2DM than in T1DM (p

Keywords: Oxidative stress, OS, T1DM, T2DM.