Abstract

A REVIEW ON HEPATOPROTECTIVE ACTIVITY OF PUNICA GRANATUM LINN

Prashant R. Shirode*, Sonali R. Musmude, Shital A. Magar, Santosh Tambe and S. Sisodia

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Abstract

This review article focuses on the hepatotoxic substance, chemicals, various reasons contributing to liver ailments causing fatal effects. It presents a number of drugs, herbal formulations and their mechanism in causing liver injuries. Alongside this article also proposed various plants, herbs, synthetic products which alters the toxic hazards caused to liver, one of which is Punica granatum (pomegranate).The chemical constituents present in punica such as polyphenols, alkaloids, flavonoids and their wide range of therapeutic effects mentioned here, further the role of antioxidant property of punica plays a vital role in hepatoprotective activity of Punica granatum.

Keywords: Punica granatum, Alanine transaminase (ALT), Alanine phosphatase (ALP), Aspartate aminotransferase (AST), Superoxide Dismutase (SOD), Tumor Necrosis Factor (TNF alpha), Interleukins (IN?s).