Abstract

CRITICAL REVIEW ON THERAPEUTIC AND TOXICOLOGICAL ASPECT OF UPVISHA: JAYAPALA (CROTON TIGLIUM)

*Dr. Arvind Tumram and Dr. Kundan Meshram

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Abstract

Ayurveda is the one of the ancient science known to human being which still providing the knowledge about various diseases and their cure. Agadtantra is one of the incredible branch among Astangas mentioned in Ayurveda which is used for diagnosis of poison and their management. Plants are the prime source of medicine in Ayurveda. Several compounds have been isolated from medicinal plants and introduced for the service of mankind; however most of these medicines have been withdrawn due to their toxicity or side effects. These poisonous/toxic plants are categorized as viṣa (poison) and upaviṣa (toxic but not lethal for human health) in Ayurvedic texts and also listed in the schedule-E of Drugs and Cosmetics Act 1940. Jayapala (Croton tiglium) is one among the upavishas and a well-known plant in Indian System of Medicine. This review article includes overall information about the plant Croton tiglium, its botanical description, toxicological aspect, treatment in both Ayurveda and Modern toxicology, its purification processes along with formulations currently used to treat various disorders.

Keywords: Ayurveda, upavishas, Jayapala.