Abstract

INTRACHOLECYSTIC PAPILLARY TUBULAR NEOPLASM (ICPN) WITH LOW GRADE DYSPLASIA - A RARE CASE REPORT

Rajeswar K., Krishna Priya R.*, Sunderesh Kamal Chander U. and Jaya Ganesh

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Abstract

Intracholecystic Papillary-Tubular Neoplasm (ICPN) is a umbrella terminology recently used which includes adenomas and hyperplasia. Here we present a case of a 57-year-old female with complaints of abdominal pain in right hypochondrial region for 2 weeks associated with vomiting. CT abdomen showed a lesion in the body of the gall bladder. Extended Radical Cholecystectomy was done. Macroscopically gallbladder with segment of liver was received and cut section of gall bladder revealed a polypoidal growth measuring 1.8*1.5*1 cm in the body with an adjacent single pigmented detached lesion measuring 1*1*0.5 cm within the lumen of the gallbladder. The wall thickness measured 3 mm. Histopathological examination showed gall bladder mucosa with adjacent polypoidal neoplasm composed of tubular and papillary structures, the tubules are lined by columnar epithelium with focal area showing goblet cells and pyloric type of mucosa. Section from the detached mass also showed similar histology. No evidence of invasion was noted and a diagnosis of this recently.

Keywords: Intracholecystic Papillary tubular, Gallbladder tumors, Papillary neoplasm, Invasive lesion and adenocarcinoma.