Abstract

PATHOLOGICAL AND PHARMACOLOGICAL REVIEW OF LIVER

Rakhi A. R.*, Sruthy Jacob I., Juno S., Pooja Nair K. R., Shahina N. S., Anjana A. K.

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Abstract

In this paper we reproachfully, review anatomic, physiological, pathophysiological and pharmacological aspects in the liver. The largest gland occupying 2.5% of total body weight and providing a host of functions obligatory for maintaining normal physiological homeostasis. Most of the function of liver are discussed very detailed on this review. Hepatocellular and exocellular mechanism of the liver explain the pathophysiological regulation. Certain drugs interrupt the mitochondrial function by a dual effect by mitochondrial disruption resulting in low level of ATP production. Metabolic receptors, for which the adequate stimuli have not yet been specified, influence feeding behavior and gastric acid secretion in response to alterations in hepatic metabolism associated with changes in the supply of metabolic fuels. Directions for future research are suggested and general conclusions about the Pathological and pharmacological aspects of liver.

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