Abstract

IMPORTANCE OF NATURAL POLYMERS AS NANOPARTICLES FOR DRUG DELIVERY SYSTEM

Mohd. Vaseem Fateh*, Navin C. Pant, Nidhi Chauhan, Mridul Bhardwaj and Heena Farooqui

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Abstract

Currently, natural and synthetic polymers are typically used as a drug delivery vectors in the form of nanoparticles and size should be within the range of 1-1000 nm. Nanoparticles improved bioavailability of water insoluble drugs, carry large payloads, protect the therapeutic agents from physiological barriers, as well as enable development of novel classes of bioactive macromolecules. Nanoparticles could be fabricated in many different shape and size using a wide range of organic and inorganic materials with polymer of natural or synthetic origin. The use of nanoparticles in the drug delivery systems and nanomedicine invariably requires parenteral administration, there has been a continues to be a major need for the use of polymeric carriers that are both biocompatible and biodegradable. The objective of the review focuses the application of nanotechnology to deliver therapeutic or diagnostic agents using biodegradable polymers.

Keywords: Nanoparticles, Natural Polymer, Synthetic Polymer, Biodegradeable Polymer, Chitosan.