Abstract

STUDY OF TOTAL IGE LEVELS AND EOSINOPHIL COUNT ACCORDING TO AGE AND GENDER IN PATIENTS WITH ALLERGIC RHINITIS

Suaad A. Brakhas, Mohammed R. Atia, Youssif J. Aziz and  Sahar A. H. AL-Sharqi*

Abstract

Allergic Rhinitis is inflammatory chronic disease induced by an IgE – mediated reaction after allergen exposure in the nasal mucosa and is identified clinically by the presence of symptoms of nasal discharge, nasal itching, sneezing and / or nasal congestion. The present study was aimed to evaluate the level of serum total IgE and eosinophil percentage count and the effect of age and gender in allergic rhinitis. Total IgE and eosinophil count were done for 297 (171 males and 126 females) patients with allergic rhinitis their mean age was 34.68 ±.72 year and 50 (24 males and 26 females) healthy non- allergic individuals as control their mean age was 36.44 ±1.99 years in the Allergy Specialized Center in Baghdad /AL-Resafa from January 2013 to November 2013. The incidence of allergic rhinitis among ages more than 20 years is more common. A significant (p˂0.001) increased in the mean level of serum total IgE (271.46 ± 13.96 IU/ml) and eosinophil count percentage (4.48±0.14 %) in patients as compared to control (Total IgE 163.83± 25.65 IU/ml and Eosinophil count 2.32±0.18 %).Association of serum total IgE (˃100 IU/ml) with gender was observed in 190 patients with allergic rhinitis (104 males, 86 females). Allergic rhinitis is associated with increased of serum total IgE and eosinophil counts and their relationship with age and gender. Serum total IgE and eosinophil counts could be helpful in the diagnosis of allergic rhinitis; all patients should be made these tests.

Keywords: Serum total IgE, Eosinophils, Allergic rhinitis.