Abstract

ANTIBACTERIAL EFFECT AND RADICAL SCAVENGING ACTIVITY OF HISPIDULIN AND NEPETIN; A TWO FLVAONES FROM TARCONANTHUS CAMPHORATUS L

Wadah J.A. Osman*, Ramzi A Mothana, Omer Basudan, Mona S. Mohammed, Malik S. Mohamed

Abstract

This study aimed to evaluate the antibacterial and radical scavenging activity effects of two flavones isolated from Tarconanthus camphoratus L. Bioactivity –guided isolation of the most active extract led to isolation and identification of two flavones Nepetin and Hispidulin. radical scavenging activity was evaluated by using DPPH (1,1-diphenyl-2-picryl hydrazyl and β-carotene bleaching method, while antibacterial test achieved by using agar dilution method. The two flavones showed strong radical scavenging activity similar in effect to the standard compounds ,Moreover the two flavones showed antibacterial activity only against Gram-+ve bacteria.

Keywords: Radical scavenging activity, antibacterial, Tarconanthus camphoratus L, Hispidulin, Nepetin.