Abstract

ARTIFICIAL PANCREAS’ – A GAME CHANGER

S. Dahlia Dixcy*, Dr. P. Sharmila Nirojini, J. Bharathi, A. Asifa Shaz, V. Durga and A. G. Anjana

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Abstract

Type 1 DM is a metabolic disorder characterized by lack of insulin due to complete autoimmune destruction of the pancreas. Hence people with T1DM require intensive insulin therapy as well as glucose monitoring. Obtaining near-normal values of glucose is the main aim of T1DM treatment which still remains unachieved in most of the people with type 1 diabetes in spite of other therapies. Recent research in the field of type 1 diabetes medicinal devices has focused on improving glucose monitoring and insulin delivery devices with the goal of combining them into an artificial pancreas, closed-loop insulin administration system. Artificial pancreas system is a recent medical innovation, which helps to keep glucose levels in check, tackles hypoglycemia and is also said to be effective when compared to other devices. The employment of a control algorithm that controls insulin administration based on real-time sensor glucose readings distinguishes this unique technique from traditional pump therapy. This review is aimed to provide a detailed description about the APS system, it’s working, benefits as well as its downsides.

Keywords: Artificial pancreas, Diabetes Mellitus, Closed-loop systems, Continuous glucose monitoring, Controller, Insulin pumps.