Abstract

SYNTHESIS, CHARACTERIZATION, ANTIBACTERIAL AND CYTOTOXIC STUDIES OF SILVER NANOPARTICLES USING AQUEOUS EXTRACTS OF CRATAEVA NURVALA LEAVES - A GREEN NANO-BIOTECHNOLOGICAL APPROACH

Vinmathi.V and Justin Packia Jacob. S*

Abstract

Silver nanoparticle has attracted considerable interest due to its potential applications such as in display technologies, thermoelectric and electronic devices, optoelectronic devices and biomedicine. Metallic nanoparticles are traditionally synthesized by wet chemical techniques, where the chemicals used are quite often toxic and flammable. In the present study, we describe a cost effective and ecofriendly technique for green synthesis of silver nanoparticles from 1mM AgNO3 solution using the extract of Crataeva nurvala leaves as reducing as well as capping agent. Nanoparticles were characterized using UV–Vis absorption spectroscopy, FTIR, and SEM. SEM analysis revealed spherical nanoparticles, the nanoparticles were studied for its antimicrobial and cytotoxic effect on MCF-7, a human breast cancer cell line.

Keywords: Silver nanoparticle, Green synthesis, UV –Vis absorption spectroscopy, Scanning Electron Microscope (SEM), MTT assay.