Abstract

REVIEW ON MUCOADHESIVE BUCCAL DRUG DELIVERY IN DIFFERENT CLINICAL ASPECT

Prabukumar V.*, Sanjana N. K., Surinder Kaur, Praveen M. and Suriya Prakash Rao S.

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Abstract

Mucoadhesion is a situation in which two components, one of which is biological in origin, are kept together by interfacial forces for lengthy periods of time. Buccal mucosa, among the numerous transmucosal routes, offers great accessibility and a relatively immobile mucosa, making it ideal for retentive dosage form administration. The goal of this study is to provide a clinical overview of the work done so far in the field of mucoadhesive buccal drug delivery systems (MBDDS). Starting with a brief overview of mucoadhesive drug delivery systems, oral mucosa, and mucoadhesion theories, this article goes on to discuss the work done so far in the subject of MBDDS, categorising it according to the ailments it is intended to treat. We also look at the numerous patents, current breakthroughs, problems, and future possibilities for mucoadhesive buccal drug delivery methods.

Keywords: Buccal mucosa, Clinical perspective, Mucoadhesion.