Abstract

ACNE VULGARIS: REVIEW ON PATHOPHYSIOLOGY AND HERBAL REMEDIES

Vandana Yadav*, Pratima Katiyar, Kalpana Kushwaha, Ruchi Verma and Manish Kumar

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Abstract

Acne poses a major challenge to dermatologists due to its prevalence, complexity, and range of clinical symptoms. This is the most common skin condition, affecting indian85%of teenage boys and 80% of teenage boys, and 80% of teenage girls, and can last into adulthood. Treatment of acne with topical and systemic symptomatic medications has mild to severe side effects. Therefore, herbs and herbal preparations play an important role as alternative therapies. This article describes herbs commonly used to treat acne. Acne is a polymorphic skin disorder of the sebaceous gland unit with abnormal sebum production, characterized by both inflammatory (papules, pustules, and nodules) and non-inflammatory (acne, open, and closed) lesions. Propionibacterium acnes and staphylococcus epidermidis are common purulent microorganisms involved in the development of various types of acne treatment including long-term use of acne lysing agents, antibiotics, and anti-inflammatory agents. These are known to cause various side effects. Moreover, the long-term widespread use of antibiotics is, unfortunately. Resistant to hypersensitivity reactions affecting the liver, lungs, and side effects such as dryness, scales, erythema, burning, and itching. To avoid such adversity, traditional or herbal formulations are preferred. Herbs are safe, effective, and multifunctional. The use of bioactive phytochemicals from a variety of plants not only cares for the body and its parts, but the components it contains also affect the biological function of the skin and are the nutrients needed for healthy skin provides. In general, plants provide a variety of vitamins, antioxidants, a variety of oils, essential oils, hydrocolloids, proteins terpenoids, and other bioactive molecules that help treat acne. Ayurveda is a traditional Indian medical system. Siddha; Unani and the Tibetan system of medicine are very helpful in identifying phytochemicals in skin and body care formulation.

Keywords: Medicinal herbs, Acne, Skin diseases, Acne vulgaris, Propionibacterium acnes, essential oil, terpenoids, inflammatory, hypersensitivity.