Abstract

LIVER METASTASES FROM THYROID PRIMARY, DIFFERENTIATING FROM THYROID VARIANT OF CHOLANGIOCARCINOMA BY IMMUNOHISTOCHEMISTRY- A RARE CASE REPORT IN A TERTIARY CARE CENTER

Vanishree Murugavel, Sonti Sulochana*, Vimal Chander, Niveditha and Akilesh Ravichandran

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Abstract

Differentiated thyroid carcinoma, enclosing follicular and papillary carcinomas, has a good prognosis and long-term survival rates. Certainly, the 10-year survival rate is 80–95%. The incidence of distant metastases at the time of initial presentation of differentiated thyroid carcinoma (DTC) is 4%. Distant metastases occur primarily in the lungs (78%), followed by intrathoracic lymph nodes (58%), neck lymph nodes (51%), pleura (29%), adrenal glands (24%), liver (20%), brain (18%), heart (18%), and retroperitoneal lymph nodes (18%). The presence of distant metastases is the most significant prognostic factor and is associated with poor outcomes. Only 50% of patients survive 10 years after a diagnosis of the metastatic DTC.[1–3]

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