Abstract

A RANDOMIZED COMPARATIVE CLINICAL STUDY ON THE EFFECT OF DVATRIMSAKA GUGGULU AND RASNA GUGGULU IN THE MANAGEMENT OF GRIDHRASI W.S.R TO SCIATICA

Anu P.*, Veerakumara K. and Shrilatha Kamath

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Abstract

Objective: To compare the therapeutic effects of Dvatrimsaka Guggulu and Rasna Guggulu in reducing the signs and symptoms of Gridhrasi/Sciatica. Design: Open randomized comparative clinicalstudy with pre and post-test design. Setting: O.P.D. and I.P.D. of Sri Dharmasthala Manjunatheshwara College of Ayurveda & Hospital, Udupi. Interventions: The patients selected were randomly divided into 2 groups of 15 each by adapting the permuted block randomization method. Selected patients were treated with oral administration of Dvatrimsaka Guggulu for a period of 14 days with the Anupana of warm water in one group and another group was administered with Rasna Guggulu. Main outcome measures: Pain – Greenough and Fraser Scoring method; Stiffness, Pricking type of pain, Twitching, Functional ability by Sugarbaker and Barofsky Clinical Mobility Scale; Functional Disability by Oswestry Disability Assessment Questionnaire; Restricted Limb Movement/SLR Tests; Neurological Deficit - Herron and Turners Rating. Results: Dvatrimsaka Guggulu and Rasna Guggulu are effective in the remission of the symptoms of Gridhrasi as evidenced by statistically significant reduction in the symptom score of various subjective and objective parameters. Conclusion: The effectiveness of the Dvatrimsaka Guggulu is supremecomparing to that of Rasna Guggulu as evidenced by the various outcome measures and the statistical analysis shows that it is significant.

Keywords: Gridhrasi, Dvatrimsaka Guggulu, Rasna Guggulu, Sciatica.