Abstract

A REVIEW ON CONTROLLED AND SUSTAINED RELEASE DRUG DELIVERY SYSTEMS

Bindu Kumari*, Ayush Garg, Jayesh Dwivedi and Ranu Sharma

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Abstract

The treatment of acute diseases or chronic illnesses has been achieved by delivery of drugs to the patients for many years. These drug delivery systems include tablets, injectable, suspensions, creams, ointments, liquids, and aerosols. Today these conventional drug delivery systems are widely used. Conventional drug therapy requires periodic doses of therapeutic agents. These agents are formulated to produce maximum stability, activity and bioavailability. For most drugs, conventional methods of drug administration are effective, but some drugs are unstable or toxic and have narrow therapeutic ranges. Some drugs also possess solubility problems. To overcome these problems, controlled drug delivery systems were introduced three decades ago. These delivery systems have a number of advantages over traditional systems such as improved efficiency, reduced toxicity, and improved patient convenience. The main goal of controlled drug delivery systems is to improve the effectiveness of drug therapies.

Keywords: Sustained release, Matrix system, Controlled release, Prolonged release, Drug release.