Abstract

PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL ACTIVITY OF EXTRACT OF SOLANUM TRILOBATUM L.

N. Tensingh Baliah* and A. Astalakshmi

Abstract

Solanum trilobatum L. is one of the oldest known therapeutic herb belonging to the family Solanaceae, widely used in cough, chronic bronchitis and the leaves are cooked as vegetable. The leaf broth used as medicine for several diseases. The present investigation was undertaken to evaluate the phytochemicals screening analysis for the eleven solvent used such as methanol, ethanol, acetone, ethyl acetate, hexane, chloroform, petroleum ether, n-butanol, n-propyl alcohol, diethyl ether and aqueous broths. The extraction capacity of methanol, ethanol and acetone is higher than the other eight solvent used. The preliminary phytochemical studies showed the presence of alkaloids, saponins, tannins, flavonoids, steroids, glycosides, phenolic compounds carboxylic acid and quinine. The antibacterial activity of crude extract of S. trilobatum was studied against gram-negative bacteria such as Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae and gram-positive bacteria such as Bacillus subtilis, Staphylococcus aureus.

Keywords: Solanum trilobatum, Phytochemical analysis, Antibacterial Activity.