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World Journal of Pharmaceutical Research (WJPR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
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Abstract

CASE REPORT: TYPICAL PULMONARY ACTH SECRETING CARCINOID TUMOR IN A YOUNG MALE

Fadil Gradica*, Elona Xhardo, Daniela Xhemalaj, Ardita Koxhaj and Lutfi Lisha

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Abstract

Introduction: Carcinoid bronchopulmonary tumors represent approximately 25% of all carcinoid tumors. Typical carcinoid tumors are the most common pulmonary neoplasy seen in young patients. These tumors can have neuroendocrine activity and certain can produce specific syndroms due to excess hormons production. Ectopic Cushing syndrome is a form of Cushing’s in which a tumor outside the pituitary gland produces adrenocorticotropic hormone (ACTH). Carcinoid and small call tumors of the lung comprises half of its cases. Presentation of case: In these report, we present a case of a young adult diagnosed with a typical carcinoid tumor and a known history of Cushing syndrome. A final diagnosis of a ectopic ACTH secreting typical lung carcinoid, was deduced. Discussion: The diagnosis was made by CT-guided percutaneous transthoracic needle biopsy and serological tests. The ectopic spot was finally detected and excised surgically through thoracotomy. After six months of follow up there was no recurrence, signs and symptoms of Cushing syndrome begin to disappear. Conclusion: A carcinoid tumor may be considered a challenging disease especially functional neuroendocrine forms considering its infrequency and consecutive symptoms. Ectopic Cushing syndrome is a complicated medical problem when it comes to identification of the ectopic spot. The surgical treatment could be curative when the spot is determined.

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