Abstract

THE PATHOPHYSIOLOGICAL EFFECT OF SARS-CoV 2 INFECTION DURING WOMAN'S CHILD BEARING AGE AND PREGNANCY

Diptendu Sarkar*, Shubham Dutta, Kamalesh Das and Gopal Dev Mandal

.

Abstract

Immunity to viral infections during pregnancy is less compared to normal condition. Pregnant women are more susceptible to SARSCoV- 2 infection, due to altered cellular composition and cellular functions of the immune system. However, in pregnancy, the immune status and adverse clinical outcomes after infection need to be studied in detail. The SARS-CoV binds to ACE2 and regulates angiotensin. ACE2 is expressed in male and female reproductive organs and may influence fertility. In female it may affect the quality of oocyte and ovarian functions. However only a few studies has been reported in male with the spermatogenesis and motility of spermatozoa. The vertical transmission of coronavirus 2 is also possible in some cases as other viral infections. The studies on SARS-CoV in the child bearing age are limited that may affect pregnancy. Therefore, hospitals and the healthcare professionals needs to pay complete attention regarding individual care, equipment and in diagnostic methods.

Keywords: COVID 19, pathophysiology, placenta, pregnancy, SARS-CoV-2 infection.