Abstract

EVALUATION OF THROMBOCYTOPENIA AND ITS RESTORATION POTENTIAL BY USING THE ETHANOLIC LEAF EXTRACT OF CARICA PAPAYA.L

Rajeshwari Sivaraj*, Sri Vishnu Priya.R, Mary Suji C.M

Abstract

Thrombocytopenia happens when body makes too few platelets, or the platelets That have been trapped in the spleen, or they are destroyed. If your spleen is enlarged, that can trap platelets, and they won't move through your body. Usually, thrombocytopenia has no symptoms. But when you do have them, they can include Lowercase b in bleeding, most often from the gums or nose. Red, flat spots on your skin, about the size of a pinhead. Blotches and bruises. This study aims to evaluate the possibility of using the leaves of Carica papaya to increase the level of platelets in the cases of thrombocytopenia, to screen and quantify various metabolites present in leaves and to identify the compound involved in the synthesis and restoration of thrombocytes. It is envisaged that this study would help in a preliminary understanding of the role of papaya leaves in altering the thrombocytes counts and also to identify the specific phytochemical involved in the reaction. Comparing the two bacteria used for this study it appears that Salmonella enteritidis is much more potent in bringing down the thrombocyte levels when compared to Escherichia coli.

Keywords: Carica papaya, Thrombocytes, Thrombocytopenia, Escherichia coli, Salmonella enteritidis.