Abstract

EFFECT OF PLANT EXTRACTED SALVADORA PERSICA L.ON SOME ISOLATED PATHOGENS FROM MOUTH AND TEETH

Lika H. Mahdi, Rana Aziz, Ali Murtatha, Shatha A. Shafiq

Abstract

This study aimed on using stem of plant Salvadora persica L.which it commonly used in cleaning teeth and has highly efficiency as Antioxident Anti-inflammatoryand Antimutageneic against many pathogens. Therefore the current study included isolation and identification some pathogens from mouth and teeth and included the Staphyllococcus aureus, Streptococcus sanguis, Streptococcus salivarius and Candida albicans and test the effect of each of the aqueous and ethyl acetate extract of Salvadora persica L.in different concentrations (1000, 750, 500, 250, 125, 62.6) μg/ml on these pathogen, in addition to detect of The minimum inhibitory concentration (MIC) and the minimum bacteriosidal concentration (MBC) . The results showed that aqueous extract had antimicrobial against these isolates higher than ethyl acetate extract in all concentrations specially at 1000 μg /ml with diameter means of inhibition zones (26.5, 18.2, 11.4, 13.7) mmeter for Staphylococcus aureus, Streptococcus sanguis, Streptococcus salivarius and Candida albicans respectively compared with ethyl acetate extract (17.4, 12.1, 9.1, 8.3) mm respectively with significant differences at p˂ 0.05 . The isolates of Staphylococcus aureus were more sensitive among tested isolates.

Keywords: antimicrobial, Streptococcus salivarius and Candida albicans.