Abstract

COMPARISON EFFICACY OF PROBIOTIC VERSUS RECADOTRIL AMONG CHILDREN WITH ACUTE DIARHEA OF 2 MONTH TO 59 MONTH OF AGE

Dr. Ursila Anwer*, Dr. Nimra Zafar, Dr. Shamayal Mandokhail and Dr. Sharoon Javaid

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Abstract

Background: Diarrhea in children is one of the leading causes of fewer than 5 year mortality worldwide, being the second leading cause of death. Diarrheal diseases cause 1.5 million annual deaths globally. In Pakistan there are 500 deaths per day, and every child on average has 5-6 episodes of diarrhea annually. As there are no published guidelines available on its use, the result of our study will help clinicians for future recommendation. Objective: To comparison efficacy of probiotic versus recadotril among children with acute diarhea of 2 month to 59 month of age at. Settings: Department of Pediatrics, Balochistan Institute of Child Health Service BICHQ, Quetta. Duration: from 29th November, 2022 to 29th May, 2022. Study design: Randomized Recadotrilled trial. Methodology: In this study a total of 400 (200 in each group) were observed. Subjects were divided into two groups by lottery method (probiotic and recadotril). The other group was discharged on oral rehydration solution only. Both groups were followed up at day 4 to assess outcome. Outcome was assessed in term of duration of diarrhea and improvement in number of stools per day, at the 4th day of presentation. Results: Our study shows that in Group A mean age was 2 ± 2.8 years while in Group B mean age was 2 ± 3.1 years. In Group A 53% children were male and 47% children were female while in Group B 55% children were male and 45% children were female. In Group A 70% children had improvement in frequency of stool (

Keywords: Outcome, probiotics, acute diarrhea, children.