WJPR Citation New

  All Since 2011
 Citation  2903  2393
 h-index  27  24
 i10-index  68  60

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

A VALIDATED STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF METFORMIN AND EMPAGLIFLOZINE IN BULK AND PHARMACEUTICAL DOSAGE FORM

*Kaveri Raman Wagh, Dr. Rakesh Kumar Jat and Dr. Rashid Akhtar

Abstract

This is a simple, economic, sensitive stability indicating RP-HPLC method for the simultaneous estimation of Metformin and Empagliflozine in bulk and pharmaceutical formulation. The method was carried out on Octa-decyl C18 column (5 μm, 25 cm x 4.6 mm i.d.) using methanol: phosphate buffer having pH 3.5 in the ratio of 70:30 at a flow rate of 1.0 ml/min. The wavelength for Metformin (MET) and Empagliflozine (EPG) at 235 nm was found to be appropriate. The retention time of MET and EPG was found to be 3.15 and 6.48 min, respectively. The regression equation for MET and EPG were found to be as Y=8.288x+0.026 and Y=27.26x+38.28 with correlation coefficient (R2) 0.999 and 0.999, respectively. The developed method is found to be robust, accurate and sensitive which can be used for estimation of combination of Metformin and Empagliflozine in pharmaceutical dosage forms.

Keywords: Metformin, Empagliflozine, RP-HPLC, Simultaneous Estimation, Stability Study.


[Full Text Article]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More