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Abstract

A CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF SHASHASHRUTHYADI MALAHARA IN THE MANAGEMENT OF SADYOVRANA

Purnima Aravind* and Mahabaleshwar S.

Abstract

Management of wound probably would have been the first medico - surgical problem faced by physicians. Ever since the life originated, human being has been susceptible to injury, either from animal attacks or other causes, which made him to think about means of healing from very early stage of development. The history of wound healing is, in a sense, the history of humankind. Wounds naturally heal by themselves, unless infected. The hunter – gatherers of the ancient times incidentally would have noticed several substances of plant and animal origin would speed up the process of wound healing and reduce the pain. In the recent decades also humans are not free off injuries and accidents. They are facing new challenges day by day with the rapid mechanization and urbanization especially in developing countries. This mechanization in their busiest life schedules invariably lead to the increased accidents and injuries. Starting from a minor cut to grievous road traffic injuries needs utmost care and attention. Even a small skin abrasion if left unattended may transform into an infected wound with complications and agony. Due to the complications that accompany the acute uncared wounds, when their healing does not progress in a timely and orderly manner, they can convert into chronic wounds, which are more difficult to manage. Of the many antimicrobial agents available, povidone iodine has remained popular after decades of use for its antisepsis.[1] A very vast description of Vrana and Vranaropaka yogas have been explained in Ayurveda thousands of years ago. Acharya Sushrutha was much aware of the importance of Vrana and has given a detailed description of Vrana and its management elaborately described in Shashti upakrama.[2]Alepa is one among them. It is having the properties like –Vranaropana, Vranashodhana, Vedanahara, Shophahara.[3] An ancient Ayurvedic text named Yogamrutham mentions Shashashruthyadi malahara in Vrana chikitsa adhyaya.[4] It includes Haridra , Yastimadhu, Karpoora Madhuchishta ,Akhukarni swarasa and Tila thaila. Akhukarni or Shashashruthi is one among the ten sacred flowers of Kerala state commonly known as ‘Dashapushpam’ which are predominantly used in Ayurveda. The wound healing activity of Emilia sonchifolia in experimentally produced wounds in rats showed significant results.[5] This can be attributed to the flavanoid content of the drug. Literature studies reveals the wound healing activity of Shashashruthi. In classics Haridra has gained place in most Vrana Ropana Yogas. It is universally accepted for its antimicrobial action. Haridra is explained in the Nighantus for its Shodana, Ropana, Kushtaghna, Vishghna, Pramehahara action.It has been accepted world wide for its antimicrobial activity. Yashtimadhu is also well known for its vrana ropana and shodhana actions. Karpoora is having a soothening effect and it is sheetha veerya,vatha hara by its rasa it is sthambhaka in action so reduces the srava from the wound. Also tila taila is also having vrana ropana gunas and its antioxidant activity helps to prevent oxidative damage and promote the healing process.. An acceptable and at-hand mode of administering Shashashruthyadi malahara is to be analyzed. A near at hand wound healing agent within the reach of common population is a pressing priority. Thus, the study is intended to evaluate the efficacy of this topical preparation, Shashashruthyadi Malahara in Sadyovrana by a clinical trial.

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