Abstract

EPIDURAL TRAMADOL FOR POSTOPERATIVE PAIN RELIEF IN GYNAECOLOGICAL SURGERIES

Dr. Udaykumar Dattatray Patil and Dr. Yuvraj V. Kumbhar*

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Abstract

The study for evaluation of epidural tramadol for postoperative analgesia was conducted in the department of obstetrics & gynecology Dr. V. M. Medical College, Solapur. The study included 48 patients undergoing gynaecological surgeries. In this preliminary study 17 patients received epidural tramadol 50 mg, 14 patients received epidural tramadol 100 mg. 17 patients received 0.25% Bupivacaine 10 cc (control group). Tramadol a synthetic opioid of the aminocyclohexanol group is centrally acting analgesic which acts at opiate receptors and also appears to modify transmission of pain impulses by inhibiton of monamine reuptake and serotonergic neurotransmission, compared with typical opioid agonist such as morphine and pethidine (meperidine) tramadol have a low incidence of respiratory depression and cardiac depression and low dependence potential. The patients were posted for gynaecological surgeries. The patients were given epidural tramadol 50 mg, 100 mg and Bupivacaine 0.25%. The time of injection of drug and onset of analgesia was observed. When epidural tramadol was used on set of analgesia was between 14 to 15 minutes. Onset of analgesia with Bupivacaine 0.25% (control group) was also 14 to 15 minutes. In group 2 the mean duration of pain relief was 7.58+/- 0.69 hrs. which was significantly higher than that of control group (P

Keywords: Epidural, Tramadol, Bupivacaine.