Abstract

COMPLETE REVIEW ON FLOATING ORAL IN-SITU GEL: DATA OBTAINED FROM PAST ONE DECADE

Dr. Jyoshna PhD*, Kamalay Roopa Rani and Karcherla David Raju

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Abstract

The present review articles discuss about the. floating oral in-situ gel formation, some of the approaches through which in-situ gels can be obtained. The ‘in situ gel’ system has emerged as one of the best novel drug delivery systems; it helps for the sustained and controlled release of the drugs by its special characteristic feature of ‘Sol to Gel’ transition. Some of the polymers that are used in in-situ gelling system are guar gum, gellan gum, xanthan gum, carrageenan, xyloglucan, pectin, chitosan and thiolated chitosan. It also focuses on the applications of in-situ gels that are the type of novel drug delivery systems in which these systems can be formulated. This approach is useful for systemic as well as local effect of drugs administered. Some of the novel drug delivery systems are oral, nasal, injectable and ophthalmic drug delivery systems.

Keywords: Floating, In situ Gels, Novel Drug Delivery, Polymers.