Abstract

ANALGESIC ACTIVITY OF HYDRO-ALCOHOLIC LEAF EXTRACT OF ACACIA NILOTICA

*Kotresh Yaligar and B. Madhulatha

.

Abstract

The present study was aimed to investigate Preliminary Phytochemical Investgation and Evaluation of hydro-alcoholic leaf extract of Acacia nilotica Linn (HLEAN). The plant materials was collected, aunticated and subjected for drying then made into course powder. The powder plant material is subjected to cold maceration and extracted with soxhlet apparatus by using hydro-alcoholic to get extract. This extract is subjected to Preliminary Phytochemical Investgation and pharmacological evaluation on Swiss albino mice. The acute toxicity studies were carried out to evaluate the drug’s toxicity and It shows toxicity at a dose of 3500 mg/kg b.w. The analgesic activity of leaf extract of Acacia nilotica was evaluated by using hot plate method in Swiss albino mice has been conducted at a dose of 100 and 200 mg/kg b.w respectively which shows significant level of *P

Keywords: Acacia nilotica Linn. HLEAN, Analgesic activity.