Abstract

PREPARATION AND EVALUATION OF LIPOSOMAL GEL OF LINCOMYCIN HCL

Rakesh Kumar* and C. K. Tyagi

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Abstract

The aim of the present study was to develop liposomal gel containing lincomycin. Lincomycin is used in the treatment of bacterial infections. It is used in infections of the skin such as acne (Pimples), abdomen, bone, skin, heart and soft tissues. It also used in post-operative infections. lincomycin is a drug which are known to have high solublity but low permeability. Lincomycin HCL. These drugs are available in the form of oral dosage that required a long period of time for treatment. The formulation was further subjected to their characteristic such as, viscosity, ph, conductivity, clarity, Invitro drug release, particle size, zeta potential, entrapment efficiency, % cumulative drug release etc. Overall, these results indicated that developed liposomal gel of lincomycin could have great potential.

Keywords: Lincomycin, Liposomal Gel, Entrapment.