Abstract

DRUG-INDUCED STEVENS-JOHNSON SYNDROME: A CASE SERIES.

Jatin Arora*, Usha D. S., M. R. Manisha, Tuhin Das, Subhranil Deb Roy

.

Abstract

Stevens-Johnson Syndrome (SJS) is one of the rare but life-threatning cutaneous reaction which can lead to symptoms like skin lesions, rash, hyperpigmentation of lips, blisters and various other painful symptoms. We represented five cases of SJS caused due to Nimesulide, Cefixime, Paracetamol, Ibuprofen and Allupurinol. In all the cases onset of symptoms took place after five-six days of medication administration. All the patients were treated using steriods, anti-histamines along with supportive care which included mouth wash and cream for topical application, and before initiation of therapy, the causitive medication was discontinued immediately after diagnosis. Disease prognosis was terminated in all the cases and patients wounds started healing as well. As advice patients were adviced not to consume the causitive medication prior consulting the physician to prevent the disease recurrence.

Keywords: Stevens-Johnson Syndrome, Hyperpigmentation, Steroids, Anti-histamines.