Abstract

IN-VITRO ANTI-INFLAMMATORY ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES AND STEM BARK OF AGLAIA ELAEGNOIDEA

Kavitha K. V.*, Dr. Rakesh Kumar Jatt and Dr. Sambath Kumar S.

.

Abstract

The present study was aimed to rationalize the scientific basis in the uses of Aglaia elaegnoidea as anti-inflammatory agent. The plant is a phytotherapeutic plant used in traditional medicine that is thought to contain active ingredients that aid in the treatment and management of a variety of ailments. The protein denaturation method was used to assess the ethanolic extract of Aglaia elaegnoidea's leaves and stem bark's in-vitro anti-inflammatory activities. Inflammation and rheumatoid arthritis are both well-known effects of protein denaturation. Aglaia elaegnoidea leaf and stem bark extract demonstrated beneficial effects in acute anti-inflammatory property at 50, 100, 200, 400, 800, and 1600 μg/ml when compared to the standard drug Indomethacin. The plant have concentration-dependent anti-inflammatory properties. According to the results of the study, Aglaia elaegnoidea leaf and stem extract significantly reduced inflammation. Leaf extract has a greater potential for reducing inflammation than bark extract. The impact may have been brought on by Aglaia elaegnoidea's polyphenol and flavonoid concentration.

Keywords: Aglaia elaegnoidea, anti-inflammatory, protein denaturation.