Abstract

BRIEF REVIEW ON DEEP EUTECTIC MIXTURE AND ITS APPLICATION

Rajesh Ramrao Suryawanshi*, Dr. Pravin S. Kawtikwar, Ankita P. Kawtikwar, Shivani M. Suryawanshi, Vaibhav P. Patange

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Abstract

Deep eutectic solvents (DES) are a type of liquid mixture composed of solid components that exhibit remarkable properties, including high solvent capacity, biodegradability, low volatile organic compound content, and relatively low toxicity. The wide range of DES available, formed from different components and ratios, has resulted in numerous studied applications. This review focuses on the applications of DES in the health field. DES have shown promise in the development of oral liquid formulations for poorly soluble active pharmaceutical ingredients, although this area is still in its early stages. We assess the potential and limitations of DES in this regard. Additionally, DES have been used as synthesis media, and we explore their use in the synthesis and extraction of bioactive natural products. Finally, we examine other exciting applications of DES in promoting health, such as their use in genomics studies, as nano-carriers for the encapsulation of anticancer drugs, or in the stabilization of medical samples.

Keywords: Deep eutectic solvent, Hydrogen bond acceptor, Hydrogen bond donor, drug delivery systems.