Abstract

MICROSPHERES AS DRUG DELIVERY SYSTEM

Prachi Jagdish Salwatkar*, Arun M. Mahale, Vrushabh Dipak Boralkar

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Abstract

"Oral modified-release multiple-unit dosage forms have been found to be more effective than conventional or immediate release single-unit dosage forms. In order to create the final dosage form, the multiparticulates are typically formulated into microspheres and then filled into hard gelatin capsules. Microspheres have been widely studied not only for their ability to provide prolonged release, but also for their potential to target specific drugs. In the future, microspheres are expected to play a central role in novel drug delivery, particularly in areas such as diseased cell sorting, diagnostics, genetic materials, and targeted drug delivery. The purpose of this review is to examine various aspects of the microparticulates drug delivery system, including formulation methods, evaluation, and characterization."

Keywords: Microspheres, Controlled release, Novel Drug Delivery, Therapeutic Efficacy.