Abstract

ORGANOGEL A PROMISING DRUG DELIVERY SYSTEM: FROM THEIR COMPONENTS TO THEIR APPLICATIONS IN DRUG DELIVERY

Mr. Mayuresh Ramesh Redkar*, Ms. Diptee Prakash Parulekar, Mr. Prajyod Deepak Haryan, Mr. Shailesh Annaso Bhandigare, Ms. Deepashree Dilip Dalvi, Ms. Minal Mangesh Walawalkar and Dr. Vijay Arjun Jagtap

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Abstract

A three-dimensional network of interlaced, self-assembled gelator fibres immobilises an organic liquid phase in organogels, which are semi-solid systems. These systems appear solid-like and have rheological behaviour despite being primarily liquid in composition. With active ingredients given via transdermal, oral, and parenteral routes, they are used as medication and vaccine delivery systems in pharmacology. The hazardous properties of the chosen organic solvents, however, have historically prevented their use as drug delivery systems. The recent synthesis of more biocompatible organogels has facilitated the development of several biological and pharmacological applications. The purpose of this article is to present a thorough overview of organogels, with a focus on the kinds, characterisation, preparation, and usage of organogels as drug delivery platforms for active agent administration through various such as transdermal, oral, and parenteral is then discussed.

Keywords: Organogels, Colloidal Drug Delivery, Gel, Drug Delivery.