Abstract

COMPREHENSIVE REVIEW ON WOUND HEALING

Samiksha Deokar, Advait Chautmal, Ritu Chavan and Devendra Shirode*

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Abstract

Wound is defined as the loss of epithelial tissue integrity. Which process four physiological steps for wound healing i.e. hemostasis, inflammation, proliferation, and remodeling. When healthy volunteers face these physiological changes, sometimes these processes are slowed down, leading to chronic or difficult-to-heal wounds. In this concern, chronic wounds is being rising every year. Addition of the inflammatory response and other complication makes delay healing process. To address the chronic wound environment and achieve skin tissue regeneration, a number of cutting-edge medical products, including wound dressings, wearable wound monitoring, negative pressure wound therapy devices, and surgical sutures, have been developed. The majority of medical devices made of both natural (chitosan, keratin, casein, collagen, hyaluronic acid, alginate, and silk fibroin etc) and synthetic materials (polyvinyl alcohol, polyethylene glycol, polycaprolactone, and polylactic acid), including bioactive molecules are support to wound healing. This review will help to highlight the various wound types and the development of wound coverings, which can accelerate to understand the wound healing and its complications.

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