Abstract

ASSESSMENT OF RISK FOR MAJOR ADVERSE CARDIAC EVENTS IN ACUTE CORONARY SYNDROME RECEIVING PERCUTANEOUS CORONARY INTERVENTION - A REVIEW

L. N. Sai Priya Kanajam*, Katari Vedha Sri, Medepalli Prasanthi, Kokkiligadda Sreevalli, K. Puroshothama Reddy and Kantamaneni Padmalatha

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Abstract

Acute coronary syndrome is a medical emergency that needs to be identified and treated immediately since it frequently results in severe chest pain or discomfort. Active smoking, metabolic syndrome, diabetes, and hypertension are common risk factors among symptomatic Acute coronary syndrome (ACS) patients. Acute coronary syndrome (ACS) patients with symptomatic carotid stenosis who have recently undergone percutaneous transluminal coronary angioplasty (PTCA) are always categorised as being at high risk for surgery because they need to continue receiving dual antiplatelet therapy. In order to compare the prognostic performance of three major risk scoring systems, including the global registry for acute coronary events (GRACE), thrombolysis in myocardial infarction (TIMI), and prediction of 30-day major adverse cardiovascular events following primary percutaneous coronary intervention (RISK-PCI). The only scoring method that could anticipate recurrent ischemia necessitating Target vessel revascularisation (TVR) was RISKPCI. The most precise system for determining the risk of acute myocardial infarction (AMI) is the Global Registry of Acute Coronary Events (GRACE) score. However, it is unclear whether GRACE score is applicable to the present patients with a high prevalence of emergent Percutaneous Transluminal Coronary Angioplasty(PTCA) and vasospasm. In patients with non-ST elevation acute coronary syndrome (Non-ST ACS), GRACE, TIMI, and HEART scores have been shown to be reliable predictors of significant adverse outcomes. For determining the prognosis in non-ST-elevation acute coronary syndrome (NSTE-ACS), the GRACE and TIMI scores have received strong validation. To analyse the relationship among clinical scores (TIMI, GRACE, and HEART) and the degree of anatomical complexity as evaluated by the SYNTAX score in patients with non-ST ACS who are undergoing cinecoronariography. Moderate correlation exists between the GRACE and TIMI scores and the SYNTAX score, which measures the severity of coronary disease. They are capable of predicting obstructive CAD but not serious disease.

Keywords: Major Adverse Cardiac Events, Percutaneous Transluminal Coronary Angioplasty, Acute Coronary Syndrome.