Abstract

EVALUATION OF NEPHRO-PROTECTIVE & CURATIVE EFFECT OF IKSHUMOOLA (SACCHARUM OFFICINARUM LINN) IN ALBINO RATS

Dr. Dattatraya S. Katkar*, Dr. Supriya Katkar and Dr. Agadrao Aoughade

.

Abstract

The plant sacchrum officinarum Lin. (family Graminaceae/ Poeceae) is commonly known as Sugar cane in English. It is bambuseae shrub, stem up to 6 meter high many nodded glabrous. Leaves long with sharp edges. Flowers flossy and root gray to blackish brown fibrous roots. This plant is explained by Sutrasta in Susharuta Samhita in the group of five drug call it as “Trunapanchmoola”. Which is diuretic in action and also used in the management of oligouria. To evaluate Nephro-protective and curative effect of Ikshu (Saccharum officinarum Linn.) moola Kwatha in Gentamicin induced Nephro-toxicity in Albino rats. To observe the side effects if any. The kidney damage was evidenced by elevated level of serum urea, serum criatinine, and electrolytes, urineproteins, and pH and by histopathological observations of kidney sections. The nephro-curative activity found prolonged in Kwatha (1.9 ml /200g rat) of Ikshumool (Saccharum officinarum Linn.) plant as it significantly reduced these evaluated levels as compare to protective group. Histopathological observations also confirm the Nephrocurative activity of Saccharum officinarum Linn. root Kwatha in albino rats.

Keywords: Saccharum officinarumLinn; Nephro- protective and curative; Ikshu (Saccharum officinarum Linn.) moola Kwatha; Gentamicin.