Abstract

EVALUATION OF ANTIMICROBIAL ACTIVITY OF ETHANOLIC EXTRACTS OF BARLERIA PRIONITIS LINN AND PHYLLANTHUS ACIDUS

Boopathi T.*, Parthiban S., Abirami G., Dina S., Praveen L. and Yamuna V.

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Abstract

In this study, we assessed comparative antibacterial and antifungal effects of extracts from Barleriaprionitislinn and Phyllanthusacidus. Antimicrobial activity was done by agar well diffusion method. The study indicated that ethanolic extract of Barleriaprionitis was more effective against fungal and bacterial species showing highest inhibition such as 18mm against fungi A.niger and 15mm against C.albicans and 22mm against bacteria Streptomyces fulvissimus and 21mm against E.coli and Bacillus subtilis. The ethanolic extract of Phyllanthusacidus showed more activity against bacteria such as 15mm against B.subtilis and 13mm against Streptomyces fulvissimus and lowest activity fungus such as 12mm against C.albicans and 10mm against A.niger. The overall evaluation studies showed that the ethanolic extract of Barleriaprionitis showed highest degree of antibacterial and antifungal activity than ethanolic extract of Phyllanthusacidus.

Keywords: Antimicrobial activity, Agar well diffusion method, Barleria prionitis, Phyllanthus acidus, Ethanolic extracts.