Abstract

IONTOPHORESIS DRUG DELIVERY SYSTEM: A REVIEW

Kalyani Kate*

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Abstract

The goal of iontophoresis drug delivery system is the permeation of ionized drug molecules across biological membrane under the influence of electric current. The objective of iontophoresis is to provide excellent therapeutic management. The drug transport through iontophoresis was established to be near 10 to 2,000 time more than easy form of delivery. This technique make possible movement of ions across a membrane under influence of externally applied electric potential difference. The rationalae behind using this technique is to reversibly alter the barrier properties of skin which could possibly improve the penetration of drug to increase systematic delivery with control input kinetic and minimum intersubject variability. For permeation of ionic and non ionic drugs the delivery system of iontophoresis use as driving force to make better delivery rate of ionic compund. iontophoresis system is cleaved in this field design. In this review given introduction, principal, mechanism. Advantage, Disadvantages and It's applications.

Keywords: Iontophoresis, Penetration enhancer, Stratum corneum.