Abstract

FORMULATION AND EVALUATION OF ANTI-DANDRUFF SHAMPOO FROM THE METHANOL EXTRACT OF DELONIX REGIA (BOJER EX HOOK.) RAF. LEAVES

Meena V. and Palaniswamy R.*

Abstract

An infection of the scalp caused by the yeast Pityrosporum is called dandruff. Dandruff is caused primarily by bacteria (Staphylococcus aureus) and fungus (Candida albicans). This fungus produces dandruff that changes the normal excretion of dead cells. In order to effectively manage and control dandruff, it cannot be completely eliminated. The purpose of shampoo is to remove surface grease, dirt, and skin debris from hair shafts and scalps without harming the scalp or hair by using suitable surfactants (surface- active materials) in liquid, solid, or powder form. Dandruff can be treated with a variety of anti-fungal agents. Synthetic shampoos are known to cause side effects including hair loss, increased scaling, scratching, nausea, and headaches. Due to this, herbal anti-dandruff shampoo was developed which is safer than chemical-based anti-dandruff shampoo in terms of health and treatment of dandruff. In herbal shampoos, the leaves extracts of Delonix Regia and other ingredients are used. In this study, a number of approaches like phytochemical analysis and Thin Layer Chromatography (TLC) are used to separate bioactive compounds. Anti-oxidant activity to detect free radicals and FTIR to identify the functional group in the sample was used. Anti-bacterial and Anti-fungal activity is used to determine whether a sample eliminates or inhibits the growth of bacteria and fungi. Few criteria are used to evaluate the shampoo formulations, including physical appearance, pH, consistency, colour and foam productivity.

Keywords: Scalp, Dandruff, Shampoo, C. albicans.