WJPR Citation New

  All Since 2019
 Citation  7475  4312
 h-index  28  21
 i10-index  197  83

Login

Best Paper Awards

World Journal of Pharmaceutical Research (WJPR) will give best paper award in every issue in the form of money along with certificate to promote research activity of scholar.
Best Paper Award :
Dr. Dhrubo Jyoti Sen
Download Article: Click Here

Search

Track Your Article

Abstract

A RECENT ADVANCES IN THE ANTIBACTERIAL POTENTIAL OF SULFADIAZINE: A REVIEW

Neeraj Kumar*, Rajneesh Kumar Gupta and Amresh Gupta

.

Abstract

As a sulphonamide, sulfadiazine is formed when a 4- aminobenzenesulfonamido group is attached to the 2-position of pyrimidine. This review was based on the recent advances in the antibacterial potential of sulfadiazine for that an extensive literature survey was done. It acts as an antibiotic, an anti-infective, an antiprotozoal medication, a coccidiostat, a xenobiotic, a pollutant in the environment, and a drug allergen. It is a sulphonamide antibiotic, a modified aniline, and a pyrimidine. It shares some properties with a sulphanilamide. Sulfadiazine is an effective sulphonamide antibacterial medication for treating low- and moderate-severity infections caused by sensitive microorganisms. Sulfadiazine is effective against Chlamydia trachomatis but has little effect on other staph infections. Many protozoa are susceptible to sulphonamides, and they are effective against them. The bacterial enzyme dihydropteroate synthetase is essential for the synthesis of dihydrofolic acid, and it is inhibited by the sulphonamides, which are structural analogues of para-aminobenzoic acid (PABA). Sulfadiazine belongs to sulphonamide category of antimicrobials. Antibacterial activity of sulfadiazine has been well confirmed from the above literature survey which used in different dosage forms i.e., ointment, nano emulsion etc. It has exhibited for increased level of efficacy at different microbial strains. Due to its severe toxicity, sulfadiazine is prescribed with precaution in the cure of microbial infections. In concludes, sulfadiazine is old but effective antimicrobial agent that can be used in transdermal patch or film dosage form too.

Keywords: Sulfadiazine, Antibacterial, Toxicity, Antibiotic-resistant, Metals.


[Full Text Article]  [Download Certificate]

Call for Paper

World Journal of Pharmaceutical Research (WJPR)
Read More

Email & SMS Alert

World Journal of Pharmaceutical Research (WJPR)
Read More

Article Statistics

World Journal of Pharmaceutical Research (WJPR)
Read More

Online Submission

World Journal of Pharmaceutical Research (WJPR)
Read More