Abstract

AN OVERVIEW OF MUCORMYCOSIS

Prof. Ashwini Shrikrushna Taware*

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Abstract

Mucormycosis is an emerging fungal infection worldwide, with devastating disease symptoms and diverse clinical manifestations. The most important underlying risk factors are immunosuppression, poorly controlled diabetes, iron overload and major trauma. The clinical presentation of mucormycosis is initially indistinguishable from other common infections, and if not diagnosed early and aggressively treated, it is almost always fatal. Early diagnosis is critical to patient survival but, unlike Aspergillus diseases, where a number of CEmarked or FDA-approved biomarker tests are now available for clinical diagnosis, similar tests for fusariosis, scedosporiosis and mucormycosis remain experimental, with detection reliant on insensitive and slow culture of pathogens from invasive Broncho alveolar lavage fluid, tissue biopsy, or from blood. This article shortly explains the types of mucormycosis, clinical manifestations and risk factors, etiopathogenesis of mucormycosis, transmission of mucromycosis, clinical manifestations or side effects of mucormycosis, diagnosis, treatment, and recent advances in the management of mucormycosis.

Keywords: Mucormycosis, Risk factors, Etiopathogenesis, Diagnosis, Treatment, Recent advances.