Abstract

FORMULATION AND EVALUATION OF HERBAL CREAM CONTAINING EXTRACTS OF HYPTIS SUAVEOLENS AND MURRAYA KOENIGII

Pooja Dhamale*, Ayodhya Tanaji Pardhe, Shubhangi Manikpuriya, Dr. Gajanan Sanap, Krishna Khadekar and Komal Jangle

Abstract

Herbal medicines are being used by about 80% of the world population primarily in the developing countries for primary health care. Herbal Plants such as Murraya Koenigii and hyptis suelovaceae traditionally used for the treatment of antimicrobial activity. In the present investigation an attempt was made to prepare and evaluate the herbal cream comprising extracts of Murraya Koenigii and hyptis suelovaceae. The herbal cream namely F1 to F4 were formulated from the ethanol extract of Murraya Koenigii and hyptis suelovaceae. The extraction was done by the Soxhlation process. Formulation of Herbal Skin Cream for antibacterial and anti-acne was successfully developed that met the relevant pharmaceutical characteristics. The prepared formulations are then evaluated for parameters like physical properties, pH, viscosity, Spreadability and stability of the formulated cream. The prepared formulations showed good Spreadability, no evidence of phase separation and good consistency during the study period. Stability parameters like visual appearance, nature, viscosity and pH of the formulations showed that there was no significant variation during the study period. The prepared formulations showed proper pH range that is approximately pH 6; it confirms the compatibility of the formulations with skin secretions. The creams were found to be stable during stability to ICH guidelines (40±2 °C/ 75±5 % RH) for 3 months. Now it can be possible to develop creams containing herbal extracts and can be used as a barrier to protect skin from achne or pimples.

Keywords: Hyptis suelovaceae, Murraya koenigii, Terpenoids, Stearic acid, Borax.