Abstract

FORMULATION AND EVALUATION OF CHOCOLATE CONTAINING ALBENDAZOLE AND IVERMECTIN

L. Gopi*, V. Ramya, S. Sandhiya, B. Rohini, S. Sandhiya and R. Reshma

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Abstract

Chocolate has been known for its good taste and proposed health effects for centuries. Most of the drugs are bitter due to which oral administration of these drugs leads to patient incompliance especially in children. The objective of the present study is to develop a chocolate formulation of Albendazole and Ivermectin for pediatric administration. The formulation consists of developing a chocolate base containing a cocoa powder, cocoa butter, normal butter, and icing sugar Thereafter drug is incorporated to above prepared chocolate base. From among the entire batches, formulation F2 albendazole showed 98.54% drug release at 45 minutes and F2 ivermectin showed 99.61% drug release at 40 minutes.

Keywords: Chocolate, Albendazole, Ivermectin.