Abstract

ASSESSMENT AND MONITORING OF ADVERSE EFFECT OF RANITIDINE WITH PHARMACOVIGILANCE STUDY

Sanika Kate, *Vishal Bodke, Ruchita Badekar, Paresh Bagul, Prajval Birajdar and Pavankumar Dhoble

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Abstract

In pharmacy profession Pharmacovigilance (PV) is essential in the healthcare profession because this examines, monitors, and identifies medication interactions and their impacts on individuals. Biotechnological and pharmaceutical treatments are designed to treat, prevent, or cure diseases, but they come with risks, chief among them the potential for adverse drug reactions (ADRs), which can be significantly detrimental to patients. As a result, it is crucial to keep an eye on pharmaceutical adverse drug reactions (ADRs) for every medicine throughout the course of its development, including in early stages of substance development, clinical studies, and post-marketing surveillance. The identification, assessment, understanding, and avoidance of ADRs are all things that PV is concerned with. Ranitidine is a drug used to reduce the formation of stomach acid and is marketed under the brand nam es Zantac and others.[4] It is frequently employed in the treatment of Zollinger-Ellison syndrome, gastroesophageal reflux disease and peptic ulcer disease.[4] It can be administered orally, intravenously, or intramuscularly. Ranitidine products from several manufacturers were recalled in September 2019 after the possible carcinogenic N-nitroso dimethylamine (NDMA) was found in them.

Keywords: Pharmacovigilance, Ranitidine, Antacid, Zantac.