Abstract

HERBAL DRUGS FOR NEUROPROTECTION IN ISCHEMIC STROKE

*Nihar Ranjan Kar

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Abstract

Ischemic stroke is a leading cause of disability and mortality worldwide. Due to the limited effectiveness and likely detrimental effects of conventional therapies claiming long-term brain benefits, alternative neuroprotective drugs need to be studied. Ischemic stroke therapy alternatives derived from natural plant herbs and pharmaceuticals are gaining attention due to their wide range of bioactive components and long tradition of medical use. In this review article, comprehensive overviews of many natural plant herbs and their derivatives that have shown promise in the treatment of ischemic stroke have been provided. This review also discusses the mechanisms of action and clinical applications of herbal drugs used for neuroprotection, as well as the preclinical and clinical evidence supporting their use in the treatment of ischemic stroke. This review also highlights the use of certain recently developed herbal drugs in the treatment of ischemic stroke. The main motto of this review focuses on the effective treatment of ischemic stroke by plant-based medications.

Keywords: Ischemic stroke, Pathophysiology, Etiopathology, Conventional Therapies, Limitations, Recent neuroprotective herbal drugs.