Abstract

ROLE OF HOMOEOPATHIC MEDICINE CARICA PAPAYA MOTHER TINCTURE IN IMPROVING PLATELET COUNT IN CASES OF DENGUE FEVER- AN ADD-ON RANDOMISED SINGLE BLIND PLACEBO CONTROLLED TRIAL

Dr. Atul Kumar Singh*, Mathur G., Mehrotra S. and Rawat S.

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Abstract

Dengue, a very widespread mosquito-borne infectious disease caused by ADES AEGYPTI virus, has been occurring during the monsoons every year.[1] The prevalence and incidence of dengue fever and death due to its complications have been increased drastically in these recent years in Bangladesh, Philippines, Thailand, Brazil, and India. Although the infection affected a large number of people around the world, there is no established specific and effective treatment by synthetic medicines. Dengue virus has four serotypes (Dengue virus-1 to Dengue virus-4) and a certain individual can be infected multiple times due to the different types of virus.[2] previously several studies were done to review the existing literature on therapeutic potential of Carica papaya leaves against dengue associated thrombocytopenia and anti-DENV potential. Bok et al. (2020)[3] in their literature review titled as “The plausible mechanisms of action of Carica papaya on Dengue infection: A comprehensive review” discussed the findings of the existing data from clinical studies. Pentewar et al. (2017)4 briefly described dengue management, thrombocytopenia manifestation in dengue and role of papaya leaves extract in dengue infection in their literature review titled as “Papaya Leaf Extract To Treat Dengue: A Review”. Two systemic and meta-analyses were made, reviewing the findings of the clinical studies and dosage safety (Charan et al., 2016; 5Rajapakse et al., 2019). 6HomoeopathicallyCarica papaya mother tincture is being used clinically to treat patients suffering from Dengue infection. Thus, this study is an attempt to assess the role of Carica papaya in mother tincture in a placebo controlled design to know whether Carica papaya homeopathic medicine is effective in improving Platelet count in cases of Dengue infection or it has a Placebo effect.

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