Abstract

PREPARATION OF CHANDRAMRUT RAS AND ITS ANTIMICROBIAL ACTIVITY (IN VITRO)

Aditi Varekar* and Sheela Pargunde

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Abstract

In Ayurveda Kaas is a disease as well as a symptom presented in many diseases, including recent situations like the COVID-19 pandemic. Every human being faces kaas (cough) in many stages and phases of life. The present study was conducted to analyze Chandramrut Ras physico-chemically, as mentioned in Bhaishajyaratnavali-Kaas rogadhikara. It is a herbo-mineral combination that acts on kaas by normalizing the functions of vaat and kapha, boosting digestive fire, and helping to increase immunity. Drugs in Chandramrut Ras like pippali, shunthi, and tankan show antimicrobial activity. Hence, Chandramrut Ras is prepared according to textual reference and then subjected to analytical testings. After that, antimicrobial activity of the drug Chandramrut Ras was seen on Gram-positive bacteria (Staphylococcus aureus) against the standard drug amoxicillin. According to a current research study, Chandramrut Ras showed antimicrobial activity on Staphylococcus aureus. It is necessary to develop a drug like Chandramrut Ras, which is a safe and potent alternative to antibiotics.

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