Abstract

COMPARATIVE STUDY OF IN-HOUSE AND MARKETED PREPARATION OF POLY-HERBAL CREAM USED FOR ANAL INFLAMMATION IN MICE

*Jija Lode, Dindayal Darunde and Sandip Umare

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Abstract

The present study was to compare the in-house and marketed formulations. The cream was formulated using medicinal plants like Til oil (Seasamum indicum), Jastamadhu (Glycerrhiza glabra), Babool sal (Acacia Arabica), Lodhra sal (Symplocos Racemosa), Pipal sal (Ficus Relogiosa), Wat sal (Ficus bengalensis), Udumber sal (Ficus glomerata), Haldi (Curcuma/onga), Madh (MeD, Khas (Andropogam Muricatus). The formulation was studied to compare the efficacy of the in- house and marketed formulation using a suitable animal model. From the biochemical assessment, histopathological study and pharmacological evaluation of the tested formulation, it was found that the marketed formulation exhibited the strongest anti- inflammatory property which was quite comparable to the in-house formulation.

Keywords: Polyherbal cream, Anal Inflammation, comparative study, croton oil, Curcuma.