Abstract

NANOSUSPENSION: A COMPREHENSIVE REVIEW ON INTRODUCTION, METHODOLOGY, REQUIREMENT AND CHARACTERISATION

Bhawani Gautam*, Jaskaran Singh Arora and Parag Patil

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Abstract

Nanosuspensions are critical carriers in the development of new medication formulations. Because of their diverse properties and unique advantages, nanosuspensions have emerged as a viable technique for the proficient conveyance of hydrophobic medicines. Due to their cost adequacy and innovative effortlessness when contrasted with liposomes and other colloidal medication transporters, nanoscale frameworks stand out enough to be noticed as a way to tackle solubility difficulties. This review paper examines nanosuspension manufacturing methods, characterization techniques, applications, and patented goods to handle the issue of inadequately water-soluble medicines. There are two basic ways to make nanosuspension: „bottom-up‟ and „top-down‟ mechanisation. Stabilisers, organic solvents, cryoprotectants, pH adjusters, buffers, polyols, salts, and osmogent can be used to make nanosuspension, as can stirring speed, temperature, and additives such as stabilisers, organic solvents, cryoprotectants, pH adjusters, buffers, polyols, salts, and osmogent. Nowadays, nanosuspension is popular and used for targeted drug delivery systems.

Keywords: Nanosuspension, Solubility, Bioavailability, Agglomeration, Nanoparticles, Mechanisation.